The COVID-19 pandemic, epidemics such as HIV/AIDS, H1N1 and other chronic diseases have impacted Latinx populations disproportionately–unveiling the sometimes inhuman condition in which they live, work and die. Yet when responses to Latinx health disparities have received mainstream attention, they are often turned into projections of individual incompetence and cultural difference–responses that minimize the structural roots of these conditions. For this reason, our work highlights the legacies, past and present, of Latinx organizing to confront such inequalities–from challenging housing conditions, labor exploitation, environmental injustice, access to education, inadequate infrastructure. In our work, challenging standardized meanings of health towards a more critical definition is a necessary and urgent imperative–that will impact the next generations of Latinx youth and children.